Strong
Fibre is the finding that holds up
Dose-dependent reductions in all-cause and cause-specific mortality across meta-analyses. Most Europeans eat about half the recommended intake.
L'asse intestino-cervello, separato dal marketing
L'asse intestino-cervello è reale. Quasi tutto ciò che viene venduto sulla base di esso è in anticipo di anni rispetto alle evidenze umane — con una grande eccezione.
81peer-reviewed citations
42European languages
0sponsored verdicts
The short version
Fibre has large, consistent, dose-dependent effects on hard outcomes and almost nobody eats enough of it. Probiotics have small and inconsistent effects on mood. Microbiome testing services have essentially nothing. The gap between those three statements is the whole story of this field.
Weak
Do probiotics affect mood?
Meta-analyses find small effects on depression and anxiety symptoms, in trials with real quality problems.
Mechanism
What the axis actually is
Vagal signalling, microbial metabolites and immune pathways — most of it characterised in rodents.
Caution
Why your microbiome test tells you nothing
There is no validated healthy reference microbiome, and results vary by sampling and sequencing method.
Letture correlate
Weight Loss Evidence
Diets, drugs, behaviour and maintenance — ranked by the strength of the evidence behind them.
Celiac Wire
Coeliac disease news, guidelines and research — plus the practical business of eating.
The Book Verdict
Health, science and self-improvement books fact-checked against the literature they cite.
IBD Evidence
Crohn's disease and ulcerative colitis — guidelines, biologics, diet and the trigger-food question.
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