Probiotisk stamme
Lacticaseibacillus rhamnosus GG: hvad den er god til
Probiotisk evidens er stammespecifik. Hvad der er sandt for LGG, er ikke automatisk sandt for andet, der deler dets artsnavn.
Hvad den er undersøgt for
En af de mest afprøvede stammer, der findes, med metaanalytisk støtte for at forkorte akut infektiøs diarré hos børn. [1]
Evidensen for effekt på stemning eller "tarm-hjerne"-endepunkter er langt svagere end for diarré.
Hvorfor stammekoden er vigtig
Probiotiske effekter er stammespecifikke, og det er ikke en teknikalitet. To stammer af samme art kan variere i, hvilke overfladeproteiner de udtrykker, om de overlever mavesyre, om de overhovedet klæber til tarmslimhinden, og hvad de producerer, når de er der. Et forsøg, der påviser effekt for LGG, påviser det for LGG — ikke for arten.
Den praktiske konsekvens er, at en mærkning, der kun angiver et artsnavn, ikke kan verificeres. Hvis den fulde betegnelse mangler, kan ingen offentliggjort evidens knyttes til det, der er i kapslen.
Andre stammer
- Saccharomyces boulardii CNCM I-745 — antibiotika-associeret diarré, rejsediarré.
- Bifidobacterium longum 1714 — stressrespons, subjektiv angst.
- Lactiplantibacillus plantarum 299v — IBS-symptomer, jernoptagelse.
- Bifidobacterium infantis 35624 — IBS.
- Limosilactobacillus reuteri DSM 17938 — kolik hos spædbørn.
- De Simone otte-stamme-formuleringen — pouchitis, colitis ulcerosa.
Hvad er LGG godt for?
Kan jeg erstatte med et andet mærke af samme art?
Overlever probiotika mavesyre?
Er mere CFU bedre?
References
Every citation below links to the original peer-reviewed record on PubMed or via DOI. Nothing here is a substitute for medical advice.
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Probiotic, prebiotic, and synbiotic interventions targeting the early-life gut-brain axis: A systematic review of randomized controlled trials Carnazzo SM, Vitello A, Allia F, et al. · Journal of neuroimmunology · 2026 · Systematic review DOIPubMed 42330779
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The Canadian Network for Mood and Anxiety Treatments Task Force Recommendations for the Use of Probiotics, Prebiotics, Synbiotics, and Fecal Microbiota Transplants in Adults With Major Depressive Disorder: Recommandations du Groupe de travail du Réseau canadien pour le traitement des troubles de l'humeur et de l'anxiété (Canadian Network for Mood and Anxiety Treatments, CANMAT) concernant l'utilisation des probiotiques, des prébiotiques, des symbiotiques et de la transplantation de microbiote fécal chez les adultes atteints de trouble dépressif majeur Bahji A, Brietzke E, Cooke NCA, et al. · Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2026 · Systematic review DOIPubMed 41252333Full text
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Fecal Microbiota Transplantation in Parkinson Disease: A Systematic Review, Meta-Analysis, and Meta-Regression Pereira MAOM, Tudella GCN, Klostermann AU, et al. · Neurology · 2026 · Meta-analysis DOIPubMed 42302222
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Systematic Review and Meta-Analysis of the Efficacy of Fecal Microbiota Transplantation in Parkinson's Disease: An Exploration Based on UPDRS and Cognitive Scores Liang B, Zou J, Mao X, et al. · Revista de neurologia · 2026 · Meta-analysis DOIPubMed 42411731Full text
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The Correlation Between Carbohydrate Loading Diet and Gut Microbiome: A Systematic Review El-Kholy O, Nichols L, Elsayed AAR, et al. · MicrobiologyOpen · 2025 · Systematic review DOIPubMed 40765268Full text
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The complex relationship between gut microbiota and Alzheimer's disease: A systematic review Zhou XP, Sun LB, Liu WH, et al. · Ageing research reviews · 2025 · Systematic review DOIPubMed 39662839
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Effects of Prebiotics and Probiotics on Symptoms of Depression and Anxiety in Clinically Diagnosed Samples: Systematic Review and Meta-analysis of Randomized Controlled Trials Asad A, Kirk M, Zhu S, et al. · Nutrition reviews · 2025 · Meta-analysis DOIPubMed 39731509Full text
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Gut microbiota variations in depression and anxiety: a systematic review Cao Y, Cheng Y, Pan W, et al. · BMC psychiatry · 2025 · Systematic review DOIPubMed 40312666Full text
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The Immune Mind: Linking Dietary Patterns, Microbiota, and Psychological Health Marano G, Traversi G, Mazza O, et al. · Nutrients · 2025 · Meta-analysis DOIPubMed 41515213Full text
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Exploring the gut-exercise link: A systematic review of gastrointestinal disorders in physical activity Al-Beltagi M, Saeed NK, Bediwy AS, et al. · World journal of gastroenterology · 2025 · Systematic review DOIPubMed 40539198Full text